Medical Sciences, Pharmaceutical Sciences
Title: | Potent TLR9-Selective and TLR9/7 Dual Antagonists |
Area: | Medical Sciences, Pharmaceutical Sciences |
Focus Area: | Potent TLR9 |
Patent: | US10662177 |
Social Benefits: | Potent (nanomolar IC 50) small molecule inhibitora of TLR9 and TLR7: 'ABODINIBS' and 'ADADINIBS'
, Demonstarated oral bioavailabity effiacy in human immune cells and pharmacokinetics in preclinal rodent model, Demonstrated efficacy in apreclinical model of psoriasis |
Developing Agency: | CSIR-Indian Institute of Chemical Biology (IICB), West Bengal |
Technology Readiness Index: | Technology Development |
Email: | director@iicb.res.in |
| Website Link : | http://www.iicb.res.in |
| Source (more info) : | https://t.ly/l_sb |
Brief Description
Description : | A series of potent inhibitors of toll-like receptor (TLR) 9 as well as dual antagonists of TLR9 and TLR with potential application in auto-immune disease and metabolic syndrome. |
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