Research

Medical Sciences

Title :

Prevalence, Characterization and Molecular Epidemiology of Mycobacterial Infections in free ranging Kashmir Stag (Hangul) and captive Double-humped Camel, Mithun and Yak of Eastern and Western Himalayas

Area of Research :

Medical Sciences

Focus Area :

Wildlife Health, Veterinary Microbiology, Infectious Diseases, Molecular Epidemiology

Principal Investigator :

Prof. Mohd Altaf Bhat, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kahmir (SKUAST), Srinagar, Jammu and Kashmir; Dr. Zahid Kashoo, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kahmir (SKUAST), Srinagar, Jammu and Kashmir; Dr. Tapan Dutta, Central Agricultural University, Aizawl, Mizoram; Dr. Shoor Singh, GLA University, Mathura, Uttar Pradesh; Dr. Rakesh Ranjan, ICAR- National Research Centre on Camel, Bikaner, Rajasthan

Co-PI:

Dr. Shaheen Farooq, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kahmir (SKUAST), Srinagar, Jammu and Kashmir; Dr. Abdul Mir, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kahmir (SKUAST), Srinagar, Jammu and Kashmir; Dr. Umar Zahid, Wildlife and We Protection Foundation, Srinagar, Jammu and Kashmir; Dr. Saurabh Gupta, GLA University, Mathura, Uttar Pradesh; Dr. Parimal choudhury, Central Agricultural University, Aizawl, Mizoram; Dr. Thiyam Singh, Central Agricultural University, Aizawl, Mizoram; Dr. Shyam Chaudhary, ICAR- National Research Centre on Camel, Bikaner, Rajasthan

Contact info :

Timeline Start Year :

2022

Timeline End Year :

2026

Total Budget (INR):

16,1.,206

Details

Executive Summary :

Tuberculosis (TB) is a reemerging and chronic infectious disease caused by Mycobacterium tuberculosis complex (MTBC); it affects livestock, wildlife, and humans. M. avium paratuberculosis (MAP) infection may lead to huge economic and production losses of the country. Infection of MAP in wild life may act as reservoir of infection for domestic livestock and vice versa which leads to negative energy balance and also damages immune system, making them susceptible to infections. Low attention to chronic and insidious infections, e.g., MAP, particularly in deer, yak, mithun and double humped camel could lead decline in their populations in India. In this study tests like fecal microscopy, fecal culture as “Gold standard” and other molecular tests will provide key insight into prevalence and transmission of MTBC and MAP and sequencing for the confirmation of new isolatesfrom free ranging and captive hangul and double humped camel population of Kashmir and Ladakh.

Equipments :

Achievements :

The project involved collecting fecal samples from diverse wildlife and domestic animals across Kashmir, Ladakh, and northeastern India, testing for Mycobacterium avium subspecies paratuberculosis (MAP). Samples underwent staining, PCR, culture, and antibody detection, revealing MAP prevalence of 37.8% via microscopy and PCR, with the Bison strain circulating among sheep and goats. Fecal The project involved collecting fecal samples from diverse wildlife and domestic animals across Kashmir, Ladakh, and northeastern India, testing for Mycobacterium avium subspecies paratuberculosis (MAP). Samples underwent staining, PCR, culture, and antibody detection, revealing MAP prevalence of 37.8% via microscopy and PCR, with the Bison strain circulating among sheep and goats.

Outcome/Output:

1

Organizations involved