Research

Life Sciences & Biotechnology

Title :

Investigation of possible selective estrogen receptor modulators

Area of research :

Life Sciences & Biotechnology, Computer Sciences and Information Technology

Focus area :

Bioinformatics

Principal Investigator :

Dr. Om Silakari, Associate Professor, Punjabi University (PU), Patiala

Timeline Start Year :

2012

Timeline End Year :

2015

Contact info :

Details

Executive Summary :

Computational analyses were successfully employed for the designing of seven multi-targeted agents against ITK, IRAK-4 and COX-2. The designed molecules were chemically synthesized, and extended to the in vitro biological testing against considered three protein targets. Finally, three molecules displayed good inhibitory activity against ITK, IRAk-4 and COX-2, which can be extended for further analyses in the future

Publications :

 
4

Organizations involved