Life Sciences & Biotechnology
Title : | A fluorescent cyclic peptide conjugated amphipathic-D diastereomers nanotherapeutics for an early detection and treatment of prostate cancer |
Area of research : | Life Sciences & Biotechnology |
Focus area : | Pharmaceutical sciences |
Principal Investigator : | Dr. Gurpal Singh,
UGC Assistant Professor, Punjab University |
Timeline Start Year : | 2023 |
Timeline End Year : | 2025 |
Contact info : | gurpalsingh.ips@gmail.com |
Details
Executive Summary : | Cancer remains a significant global issue, with around 28.0 million new cases expected by 2040. Prostate cancer is one of the most silent cancers, affecting approximately 30% of all major cancers in men. Detecting and treating malignant growth simultaneously is crucial for successful treatment. Current imaging methods, such as computer tomography, ultrasound, positron emission tomography, and magnetic resonance imaging, lack quantification of tumor volume. Peptide treatment offers a promising alternative due to its low molecular weight, low toxicity, and ability to specifically target cancer cells. An amide-linked fluorescent cyclic peptide-amphipathic-D diastereosmers could improve detection and treatment efficacy by expanding prognosis and repressing malignant growth progression. These nanoparticles could be entrapped in PLA-PEG to improve stability and delivery of peptide payloads to tumor environments. |
Co-PI: | Dr. Ravi Pratap Barnwal,Panjab University, Dr. santosh kumar,Post Graduate Institute of Medical Education and Research, Dr. Rakesh Kapoor, Post Graduate Institute of Medical Education and Research, Dr. Sanjay Kumar Bhadada, Post Graduate Institute of Medical Education and Research, (Chandigarh) |
Total Budget (INR): | 57,88,760 |
Organizations involved
