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US9029553: 2-anilino nicotinyl linked 2-amino benzothiazole conjugates and process for the preparation thereof

The invention provides compounds of general formula A useful as potential anticancer agents against human cancer cell lines and apoptosis inducers. It further provides a process for the preparation of 2-anilino nicotinyl linked 2-amino benzothiazole conjugates of general formula A, wherein R1dbd.H or Cl; R2dbd.H, OCH3 or F; R3.dbd.H, OCH3, F or Cl; R4dbd.H, OCH3 or F and X.dbd.OCH3, F or N02.

Filing Date: 14-08-2013

Issue Date: 12-05-2015

Applicant: CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad

Patent No: US9029553

Application No: 13/985417

Inventor(s): Ahmed Kamal, Yellamelli Valli Venkata Srikanth, Mohammed Naseer Ahmed Khan, Mohammed Ashraf, Irum Sehar, Gousia Chashoo, Parduman Raj Sharma, Abid Hamid Dar, Shashi Bhushan, Shashank Kumar Singh, Dilip Manikrao Mondhe, Ajit Kumar Saxena

IPC Classification: C07D 417/12, A61K 31/4439, A61P35/00

Country: United States of America

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