Patents

Enantioconvergent chemoenzymatic synthesis of (r)-gamma-amino-beta-hydroxybutyric acid ((r)-gabob)

The present invention particularly relates to a chemoenzymatic process for the stereoselective preparation of both enantiomers of 3-hydroxy-4-trityloxy butanenitrile key intermediates for the preparation of (R)-GABOB by lipase mediated kinetic resolution of its racemates and their effective application in the enantioconvergent synthesis of (R)-GABOB.

Filing Date: 23-12-2004

Issue Date: 20-05-2008

Patent No: US7374926 [USA]

Application No: 11/022,275

Inventor(s): Kamal, Ahmed; Khanna, Gollapalli B Ramesh; Tadiparthi, Krishnaji; Rondla, Ramu

Licensing Option: Laboratory willing to jointly develop technology with industrial partner.

Implementing institute: CSIR-Indian Institute of Chemical Technology [CSIR-IICT]

Funding agency: Council of Scientific and Industrial Research (CSIR)

IPC Classification: C12P 41/00, C12P 13/00, C12P7/00, C12P

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