Research

Chemical Sciences

Title :

Synthesis of diferrocenyl heterocycles linked by aryl spacers and their photophysical and electrochemical studies

Area of research :

Chemical Sciences

Principal Investigator :

Dr. Prabal Pratap Singh, G.L.A. University, Uttar Pradesh

Timeline Start Year :

2022

Timeline End Year :

2025

Contact info :

Details

Executive Summary :

Ferrocene, discovered by Pauson and Miller, has been a subject of interest worldwide for its various applications in natural science, asymmetric synthesis, fuel, sensors, catalyst, and electroactive materials. Recent research has focused on ferrocene hybrids with antimalarial, anticancer, antitumor, antifungal, and anti leishmanial activities. Ferrocene derivatives linked to other moiety through selected linkers have enhanced various properties, including stability to water and air, unusual redox ability, low toxicity, and versatile chemical activity. Recent studies have shown that the replacement of aryl or hetaryl nucleus with ferrocene can change the properties of bioactive compounds, such as solubility, hydrophilicity, and lipophilicity. The electro and spectroelectrochemical behavior of diverse diferrocenyl heterocyclic compounds have been published, highlighting the electron charge transfer properties of compounds directly influenced by their electronic characteristics. High porosity materials like MOFs and coordination polymers have been used in the production of electrically conductive materials for batteries and super capacitors. Tuning these materials with inorganic and organic fillers has led to promising outcomes in energy storage. Challenges include introducing ferrocene units at the opposite end of heterocyclic ring systems and optimizing mild reaction conditions for synthesis. Developing an efficient and milder synthetic route for di ferrocenyl heterocyclic compounds containing heterocyclic rings separated by five and six membered aryl or heteroaryl linkers is highly desirable. Studying the photophysical and electrochemical behavior of synthesized compounds is of great interest due to the outstanding activities recently observed for ferrocene pendant heterocycles.

Total Budget (INR):

18,30,000

Organizations involved