Research

Physical Sciences

Title :

Facile Synthesis of Multi-functional Silver Chalcogenides Quantum Dots and their Promising Biosensing Application

Area of research :

Physical Sciences

Principal Investigator :

Dr. Kusha Kumar Naik, Berhampur University, Odisha

Timeline Start Year :

2023

Timeline End Year :

2026

Contact info :

Equipments :

Details

Executive Summary :

According to the International Diabetes Federation (IDF) report 2021, about 573 million people are living with diabetes worldwide and Diabetes has been declared a pandemic which is affecting both the mentality and economic prosperity of the nations. India is considered a storehouse of Diabetes and an estimation of 77 million people in India have been affected by Diabetes. By 2045, 134 million people in India may be affected by Diabetes. Diabetes is a controllable disease and the presence of glucose in the blood is catalyzed and regulated by the secretion of insulin. So, Diabetes is not a hectic problem but the real problem is early detection and precise measurement of the glucose amount present in the blood. A lot of methods, mechanical, optical, electrical, gravimetric, and electrochemical are available to sense and enumerate the glucose quantity. But, the electrochemical method is a suitable method due to the electrocatalytic nature of biomolecules. Electrochemical detection of biomolecules offers rapid response, high sensitivity, and selectivity. Nowadays, there are many demands, curiosity, and privilege challenges to measuring the exact, accurate, and cost-effective glucose level due to its wide range of applications in health care, biotechnology, and food technology industries. Non-enzymatic glucose sensors have been considered as the fourth generation of the glucose sensor and it is based on the nanoparticles. Nanomaterials offer significant advantages owing to their small size and broad surface area which hold significant numbers of catalytic centers to communicate directly with the glucose molecules. So, the catalytic properties and the movement of biomolecule analytes increase significantly compared to macro scale materials. Silver is a costly and environmentally friendly transition metal and it can be coupled with chalcogenides to form silver chalcogenides materials. Again, pristine silver chalcogenides can be engineered by shaping their morphology and compositions. It is well known that the quantum dots (0D) of nanomaterials possess more sensational morphology than 1D and 2D nanomaterials. So, the suitable and integrated composition of multifunctional silver chalcogenides quantum dots could be synthesized by two methods, hydrothermal and electrodeposition and their collective electrochemical and biocatalytic properties towards biomolecules can be revealed to the scientific community. Electrochemical experiments like CA, CV, Interference, stability, and real sample analysis experiments can be executed to expose the catalytic properties of the synthesized materials. Exposing electrocatalytic properties of the synthesized silver chalcogenides quantum dots, not only glucose sensor industries will get the benefit but also Bioprocessing, Biotechnology, and food industries will also get benefit from the glucose sensing study. So, it is a Socio-economic relevance as well as health and technological correlated project.

Total Budget (INR):

41,10,832

Organizations involved