Industry Academia Collaborations

Antigens and proteins from liquid bio-medical waste

Separate antigens and proteins from native sources by purification of bio medical waste such as ascetic/plural fluids, HBsAg+ve blood, etc. These antigens and proteins have diagnostic importance, which are used as the basic reagents for the preparation of controls, calibrators in diagnostic kits. We focussed on three products, CRP (C-reactive Protein), CEA (Carcino-Embryonic Antigen) and CA-125 (Ovarian Cancer antigen) for worldwide market. A source of recombinant and cell derived antigens, and antibodies (polyclonal, monoclonal) for biomedical research and to develop in vitro diagnostic methods in the area of communicable and non-communicable diseases including cancers. Focus was on - Development of indigenous reagents (antigens and antibodies) for manufacturing of a wide variety of diagnostic immunoassays. Development of those RDT antigens are done by bacterial or E-Coli expressions. Development of humanized monoclonal antibody controls for diagnostic immunoassays obviating the need of human serum samples from patients for the same purpose. These will be particularly helpful in some infectious and auto-immune disorders.

Area: Life Sciences & Biotechnology

Focused Area: Diagnostic immunoassays

Alignment with SDG: SDG 3

Contact Info:

Paper Published: 5

Industry Name: M/s Yashraj Biotechnology Ltd

Industry Location: Navi Mumbai

Funding Agency: Technology Development Board (TDB)