Life Sciences & Biotechnology

Title :

Understanding the mechanism of hemoglobin receptor recycling by Rab GTPases in Leishmania donovani

Area of research :

Life Sciences & Biotechnology

Principal Investigator :

Prof. Amitabha Mukhopadhyay, Professor, Indian Institute of Technology Delhi (IITD), Delhi

Timeline Start Year :


Contact info :

Associated Programme / Scheme :

Core Research Grant (CRG)


Executive Summary :

In this study, investigators will clone and express Rab11 and Rab4 homologs from the Leishmania and try to identify their effectors. Finally, studies will be carried out to understand the role of Rab4 and Rab11 in Hb-receptor recycling pathway in Leishmania using Rab4 or Rab11 knock out parasites or parasites overexpressing dominant negative mutants of Rab4 or Rab11.


Dr C S Dey, Professor, Indian Institute of Technology Delhi (IITD), Delhi

Total Budget (INR):


Organizations involved