Life Sciences & Biotechnology
Title : | Mutagenesis of M. tuberculosis glyceraldehyde-3-phosphate dehydrogenase (M.tb GAPDH) to identify key residues involved in protein multifunctionality |
Area of research : | Life Sciences & Biotechnology |
Focus area : | Enzymology |
Principal Investigator : | Dr. Chaaya Iyengar, Assistant Professor, National Institute of Pharmaceutical Education and Research (NIPER), Mohali |
Contact info : | chaaya@niper.ac.in |
Details
Executive Summary : | To create selected mutations in the sequence of M.tb GAPDH (Rv 1436), to express and purify individual mutant proteins, and to evaluate the effect of these mutant ions on the multifunctional properties of GAPDH (i.e Transferrin binding /Plasminogen binding) |
Total Budget (INR): | 5,00,000 |
Organizations involved
