Research

Life Sciences & Biotechnology

Title :

Lipid conjugate based and nontech driven approaches for oral /systemic delivery of amphotericin B in efficient management of visceral leishmaniasis and systemic fungal infection

Area of research :

Life Sciences & Biotechnology

Focus area :

Pharmacology

Principal Investigator :

Dr. Sanyog Jain, Assistant Professor, National Institute of Pharmaceutical Education and Research (NIPER), Mohali

Contact info :

Details

Executive Summary :

Development of lipidic prodrugs of amphotericin B with improved gastrointestinal stability and permeability therefore to enhance its oral bioavailability, encapsulation of lipidic prodrug of AmB in lipid based nanodrug delivery systems with high practical drug loading, and to reduce hemolytic and nephrotoxicity of the amphotericin B

Total Budget (INR):

37,07,000

Organizations involved