Life Sciences & Biotechnology
Title : | Influence of Nrf2-ARE signaling pathways on the genetic and epigenetic modifications in the germ cells of diabetic rat: Role of zinc and selenium |
Area of research : | Life Sciences & Biotechnology |
Focus area : | Epigenetics, cell biology |
Principal Investigator : | Dr. G. B. Jena, Associate Professor, National Institute of Pharmaceutical Education and Research (NIPER), Mohali |
Contact info : | gbjena@niper.ac.in |
Details
Executive Summary : | To study the influence of hyperglycemia on the genetic and epigenetic alterations in the testicular patho-physiology of rat, to investigate the role of genetic and epigenetic alterations in the zinc and selenium supplementation in the testicular patho-physiology during hyperglycemic condition in rat, and to explore the involvement of novel testicular markers (Nrf2) in hyperglycemia as well as supplementation conditions (Nrf2 activator) and to correlate the testicular damage as well as amelioration |
Total Budget (INR): | 10,53,000 |
Organizations involved
