Research

Life Sciences & Biotechnology

Title :

Exploring the role of aging on chaperone - mediated protein folding in a yeast model of Huntington's disease

Area of research :

Life Sciences & Biotechnology

Focus area :

Protein engineering, microbiology

Principal Investigator :

Dr. Ipsita Roy, Associate Professor, National Institute of Pharmaceutical Education and Research (NIPER), Mohali

Contact info :

Details

Executive Summary :

To study the role of the glycerol synthetic enzyme, Gpd1, in aggregation of mutant huntingtin in Saccharomyces cerevisiae, to study the role of the glycerol transporter, Fps1, in aggregation of mutant huntingtin in Saccharomyces cerevisiae, and to study the effect of dietary restriction on aggregation of mutant huntingtin in Saccharomyces cerevisiae

Total Budget (INR):

26,25,000

Organizations involved