Medical Sciences

Title :

Development of SERS based ultra-sensitive, rapid, portable and field deployable platform for detection of pathogenic bacteria and Dengue virus

Area of research :

Medical Sciences, Life Sciences & Biotechnology

Focus area :

Maternal and child health, Point of care diagnostic tests and surveillance systems for common non-communicable and Infectious diseases

Principal Investigator :

Dr. J.P. Singh, Professor, Department of Physics, Indian Institute of Technology (IIT), New Delhi

Contact info :


Executive Summary :

A new handheld, field-deployable SERS based diagnostic tool having capabilities of rapid on-chip specimen separation and detection of Dengue virus and pathogenic bacteria like Staphylococcus aureus and Escherichia coli for point-of-care diagnostics will be developed. The current available methods for identification of bacteria/virus such as biochemical test, PCR are time consuming and laborious. The novel Ag nanorod based surface enhanced Raman scattering substrates fabricated by e-beam glancing angle deposition (GLAD) system will provide rapid and accurate detection of pathogenic bacteria and dengue virus. The hypothesis is that SERS spectrum provides a unique 'molecular fingerprint' of individual virus/bacteria based on their specific molecules that are in contact with metal nanoparticles without any species-specific reagents typically required for virus/bacteria signal amplification.


Prof. Prashant Mishra, Professor, Biochemical Engineering and Biotechnology, Indian Institute of Technology (IIT), New Delhi, Dr. Neena Valecha, Director & Scientist-G, National Institute of Malaria Research (NIMR), New Delhi, Dr. Deepali Savargaonkar, Scientist-D, National Institute of Malaria Research (NIMR), New Delhi

Total Budget (INR):


Organizations involved