Research

Pharmaceutical Sciences

Title :

Antibody-based capture of 2019-nCoV and its inactivation using lipid-based in situ gel

Area of research :

COVID-19 Research, Life Sciences & Biotechnology, Pharmaceutical Sciences

Focus area :

Drug repurposing for COVID-19

Principal Investigator :

Dr. Kiran Kondabagil, Associate Professor, Indian Institute of Technology (IIT), Mumbai

Timeline Start Year :

2020

Contact info :

Details

Executive Summary :

The project aims to develop antibodies against the receptor-binding domain of the spike glycoprotein of CoV involved in recognizing a host cell-surface receptor, namely, zinc peptidase angiotensin-converting enzyme 2. Another objective is to develop unsaturated free fatty acid-based emulsion loaded in-situ gels to inactivate the virus at the point of entry.

Organizations involved