Research
Title : | Sero-surveillance and molecular epidemiology studies of selected infectious diseases of the livestock in Himalayan Region |
Area of Research : | Medical Sciences |
Focus Area : | Infectious Diseases, Molecular Epidemiology |
Principal Investigator : | Dr. Mohd. Isfaqul Hussain, SKUAST-Kashmir, Srinagar; Dr. Shoor Vir Singh, GLA University, Mathura, Uttar Pradesh; Prof. Subhash Verma, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh; Prof. Tapan Dutta, Central Agricultural University, Selesih, Aizawl, Mizoram |
Co-PI: | Dr. Zahid Kashoo, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir (SKUAST-K), Kashmir, Srinagar, Jammu and Kashmir; Dr. Saurabh Gupta, GLA University, Mathura, Uttar Pradesh; Dr. Kundan Chaubey,GLA University, Mathura, Uttar Pradesh; Dr. Shaheen Farooq, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir (SKUAST-K), Kashmir, Srinagar, Jammu and Kashmir; Prof. Mandip Sharma, CSK Himachal Pradesh Krishi Vishvavidyalay, Palampur, Himachal Pradesh; Dr. Parimal Roychoudhury, Central Agricultural University, Selesih, Aizawl, Mizoram |
Contact info : | isfaqhussain@yahoo.com; shoorvir_singh@rediffmail.com; sverma8@gmail.com; tapandutta@rediffmail.com; zahidkashoo@gmail.com; saurabh.gupta@gl.ac.in; kundan.chaubey@gla.ac.in; shaheen_mvsc@yahoo.co.in; mandeepsharma289@hotmail.com; parimal74@rediffmail.com |
Timeline Start Year : | 2022 |
Timeline End Year : | 2026 |
Total Budget (INR): | 1,38,.6,172 |
Details
Executive Summary : | orth Himalayan states (Jammu & Kashmir, Ladakh, Himanchal Pradesh) are endowed with good breeds of sheep, goats, and cattle. Bio-diversity of ‘indigenous breeds’ is threatened due to endemicity production diseases (Paratuberculosis, Brucellosis & Foot rot) leading to high morbidity and mortalities in high producing breeds reared in extreme weather conditions. ParaTB is caused by Mycobacterium avium subspecies paratuberculosis. Brucellosis leads to abortion in late gestation and sterility in males. Vaccine helps to enhance productivity and reduce losses and biodiversity. Foot rot is major disease infecting sheep in temperate climate leading to production losses. Project aims to estimate sero-prevalence and molecular characterization of the isolates. Vaccination of selected farms will evaluate impact of calfhood vaccination using S19 and RB51 or Rev1. Project proposes ‘management and control of three major livestock diseases using indigenous diagnostic and vaccine technologies. |
Equipments : | NA |
Achievements : | Successfully isolated and characterized novel Mycobacterium avium subspecies paratuberculosis(MAP)‘Indian Bison type’ strain 12(1-6985) from a chronic case of buffalo suffering from diarrhoea and weakness. Developed ‘indigenous buffalo-based vaccine’ using novel MAP strain 12(1-6985);This ‘new indigenous vaccine’ will be used in our future vaccine studies on control of MAP infection in bovines (cows and buffaloes),replacing the previous‘ indigenous goat-based vaccine usingS5 strain of goat origin. Similarly, ‘indigenous ELISA kit’ using buffalo-derived MAP strain has been developed to improve the specificity and sensitivity in diagnosis of bovine Johne’s disease(BJD). Completed genome sequencing of MAP strain 12(1-6985, first fully sequenced MAP strain from clinically affected buffalo in I |
Outcome/Output: | 1 |
Organizations involved
Implementing Agency : | SKUAST-Kashmir, Srinagar, Jammu and Kashmir Funding Agency :Department of Science and Technology (DBT) | Source: E-promis and Information received by Investigator | |