Medical Sciences, Life Sciences & Biotechnology


A Promising Therapeutic Lead from Medicinal Plant: Hope for Targeting Cancer and Cancer Stem like Cells


Medical Sciences, Life Sciences & Biotechnology

Focus Area:

Cancer Treatment

Social Benefits:

In vitor studies with CM-5,Mechanism of Apotosis induced by CM-5, Toxicity of CM-5, In vivo and ex voivo studies with CM-5, Herbal extract enriched with CM-5

Developing Agency:

CSIR-Indian Institute of Chemical Biology (IICB), West Bengal

Technology Readiness Index:

Market Launch

Website Link :
Source (more info) :

Brief Description

Description :

Abundantly available across India in all seasons Lead molecule: Carbazole Alkaloid (CM-5) medicinal value reported in Charaka Samhita. Non toxic to CD34+ progenitor cell, normal blood cells and astrocytes, normal lung/kidney cell lines from human to monkey. Showed NO acute and chronic toxicity towards normal mice . Shows anti-proliferative activity against cancer cells(in vitro/ex vivo/ in vivo)

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