Medical Sciences, Life Sciences & Biotechnology


Peptide-based Delivery of Therapeutic Nucleic Acids Targeting Neurodegenerative Diseases


Medical Sciences, Life Sciences & Biotechnology

Focus Area:

Treatment of Neurodegenerative Diseases



Social Benefits:

An excellent method for delivering siRNA across the blood-brain barrier for the intervention of neurodegenerative diseases.

Developing Agency:

CSIR-Centre for Cellular and Molecular Biology (CCMB), Telangana

Technology Readiness Index:

Lab Validation

Website Link :
Source (more info) :

Brief Description

Description :

The technology pertains to the potential and utility of TARBP-BTP, a new fusion protein that fosters the efficient delivery of siRNA to the brain and hence mediate the knockdown of target genes responsible for early onset of neurodegenerative disorders and would also serve unmet needs for incurable neurological conditions. e.g. Huntington's Disease, Alzheimer's Disease (AD).

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