Medical Sciences, Life Sciences & Biotechnology


DNA Vaccine as Immune-prophylaxis Against Kala-azar


Medical Sciences, Life Sciences & Biotechnology

Focus Area:

Genetic Immunization against Kala-azar



Social Benefits:

An indigenous technology having immense prophylactic potential; WHO has identified leishmaniasis as a major and increasing public health problem. Available chemotherapeutic strategies emerging resistant strains and lack of an effective vaccine against Kala-azar intensifies the crisis; The vaccine prevents mortality of the mammal from lethal virulent Leishmania infection and confers sterile protection in tissues that would be infected by Leishmaniaupon exposure.

Developing Agency:

CSIR-Indian Institute of Chemical Biology (IICB), West Bengal

Technology Readiness Index:

Lab Validation

Website Link :
Source (more info) :

Brief Description

Description :

The technology uses a highly conserved membrane protein present in all species of Leishmania as a vaccine antigen for genetic immunization against visceral leishmananiasis or Kala-azar.

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