Agricultural Sciences, Chemical Sciences


A Mercaptan Free Process for Profenofos


Agricultural Sciences, Chemical Sciences

Focus Area:


Social Benefits:

Profenofos is very effective on cotton pests especially white fly menace and controls Lepidoptera insects and Mites in cotton, tobacco, sugar beet, soya beans, vegetables etc.

Developing Agency:

CSIR-Indian Institute of Chemical Technology (IICT), Telangana

Technology Readiness Index:


Website Link :
Source (more info) :

Brief Description

Description :

Profenofos an important member of the Organothiophosphate class of insecticides is a cholinesterase inhibitor, non-systemic insecticide and acaricide with contact and stomach poison. With a view to overcome the pollution problem and to provide a better quality product, an innovative clean, green and cost effective technology was worked out avoiding mercaptan release. IICT approach for manufacture of profenofos involves 4 steps and cheap raw materials, which are also easily available, and therefore is easy to commercialize. The product is odourless and has a better impurity profile. IICT approach is a mercaptan free route, so overcomes a major effluent and pollution problem. It is an environmentally benign and cost effective technology. Major Raw Materials to be Utilized are 2-Chlorophenol, Bromine, inorganic and organic bases, n-Propyl bromide, DETC etc. PROFENOFOS has efficacy equivalent to Monocrotofos but has higher degree of safety to mammals.

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