Life Sciences & Biotechnology
Title : | Regenerative experimental approaches for cell-based therapies |
Area of research : | Life Sciences & Biotechnology, Medical Sciences |
Focus area : | Stem cells in therapeutics |
Principal Investigator : | Vivek T Natarajan, Scientist, CSIR-Institute of Genomics & Integrative Biology (CSIR-IGIB), Delhi |
Timeline Start Year : | 2020 |
Timeline End Year : | 2025 |
Contact info : | tn.vivek@igib.res.in |
Details
Executive Summary : | Objective: Capacity building for generating engineered CART cells and their validation in preclinical models; Rejuvenate Lung Epithelium using MSC with mitochondrial transfer; Develop methods to achieve target cell regeneration in skin and lung; Directed differentiation of cells to melanocyte, hepatocyte and neuronal lineage using defined factors and model appropriate diseases in them; Re-engineer epidermal cells and evaluate matrices for regeneration in diabetic wounds; Develop assays for to assess purity and genomic integrity of cells for transplantation. |
Organizations involved
