Chemical Sciences

Title :

Computationally aided synthesis of artificial receptors: Biomimetic molecularly imprinted polymers (MIPs)

Area of research :

Chemical Sciences, Life Sciences & Biotechnology, Material Sciences

Focus area :

Artificial receptors

Principal Investigator :

Dr Shekhar Hansda, Scientist, CSIR-Central Glass and Ceramic Research Institute (CSIR-CGCRI), Ahmedabad

Timeline Start Year :


Timeline End Year :


Contact info :


Executive Summary :

Objective: Synthesis of artificial receptors: Biomimetic molecularly imprinted polymers

Summary: Producing artificial receptors alternate to biological receptor molecules such as antibodies, proteins and enzymes have major interest in many applications. Although methods have been developed to produce artificial receptor molecules, creating the artificial receptors with unique selectivity and stability which can be used in harsh environment (extreme pH, temperature, and organics solvent) is lacking. Computational approaches (density functional theory (DFT) modelling and molecular dynamics (MD)) will be utilized here to synthesis molecular imprinted polymers (MIPs), with unique stability and selectivity, alternate to biological receptors. The produced MIPs were tested for their applications in environmental monitoring, separation and diagnosis.

Organizations involved