Life Sciences & Biotechnology

Title :

Regenerative experimental approaches for cell-based therapies

Area of research :

Life Sciences & Biotechnology, Medical Sciences

Focus area :

Stem cells in therapeutics

Principal Investigator :

Vivek T Natarajan, Scientist, CSIR-Institute of Genomics & Integrative Biology (CSIR-IGIB), Delhi

Timeline Start Year :


Timeline End Year :


Contact info :


Executive Summary :

Objective: Capacity building for generating engineered CART cells and their validation in preclinical models; Rejuvenate Lung Epithelium using MSC with mitochondrial transfer; Develop methods to achieve target cell regeneration in skin and lung; Directed differentiation of cells to melanocyte, hepatocyte and neuronal lineage using defined factors and model appropriate diseases in them; Re-engineer epidermal cells and evaluate matrices for regeneration in diabetic wounds; Develop assays for to assess purity and genomic integrity of cells for transplantation.

Organizations involved