Life Sciences & Biotechnology
Title : | Exploring the Pathway of Protein Supramolecular Assembly through Machine Learning Aided Molecular Simulations |
Area of Research : | Life Sciences & Biotechnology |
Focus Area : | Computational Biology |
Principal Investigator : | Dr. M.HamsaPriya , Indian Institute Of Technology (IIT) Madras, Tamil Nadu |
Contact info : | hamsa@iitm.ac.in |
Timeline Start Year : | 2024 |
Timeline End Year : | 2027 |
Total Budget (INR): | 6,60,000 |
Details
Executive Summary : | The project intends to employ machine learning based advanced molecular simulation technique to understand the pathway of self-assembly of proteins into supramolecular structure. We would first explore the coupled dynamics of protein folding and dimerization. Then extend the study for multimeric assembly like amyloid fibril formation and protein nanocages. |
Organizations involved