Research
Title : | Targeting nucleolin for refining anti-neoplastic chemo-immunotherapy and immunomodulation in B-Cell lymphoma |
Area of research : | Medical Sciences |
Focus area : | Oncology |
Principal Investigator : | Dr Neeraj Jain, Scientist, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow |
Timeline Start Year : | 2022 |
Contact info : | neerajsbtjnu@gmail.com |
Associated Programme / Scheme : | Core Research Grant (CRG) |
Details
Executive Summary : | The study will understand in-depth functions of surface nucleolin in lymphoma biology, and this will determine alternative strategies to overcome chemotherapeutic resistance. The study will also analyses the importance of tumor cell specific surface nucleolin in maintaining stem cell phenotype and alternative strategies to target these cancer stem cell populations will be investigated. |
Co-PI: | Dr Gopal Chandra Kundu, Professor, Kalinga Institute of Industrial Technology (KIIT), Odisha, Dr Anurag Varshey, Head, University of Patanjali, Uttarakhand, Dr Manisha Naithani, Scientist, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow, Dr Naveen Kumar Singhal, Scientist, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow, Dr Uttam Kumar Nath, Scientist, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow |
Total Budget (INR): | 56,23,240 |
Organizations involved
Implementing Agency : | CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow Funding Agency :Science and Engineering Research Board (SERB), Department of Science and Technology (DST) | |