Social Benefits: | The main component plant is abundantly available plants throughout India. Novel purification protocol costs less and quick isolation. Total yield is high in EtOAc extract, which may be a useful for cancer treatment; Pharmacokinetics study indicated that the compounds are easily absorbable in blood stream and there is no production of secondary metabolites; Showed anti-cancer activity in low dose against glioma and cervical cancer cell lines Normal cells [heart, liver, muscle and peripheral blood mononuclear cells (PBMC)] showed minimum sensitivity by in vitro testing. Minimum toxic effects; This combination therapy reduced dose of highly toxic two known anticancer agent (cisplatin and paclitaxal); Multiple administration modes (oral, intravenous, intramuscular or subcutaneous rout) were available of these active components for the in vivo treatment. |
