Patents

US6734309: Process for the synthesis of isonicotinic acid hydrazide

The invention provides a process for the manufacture of Isonicotinic Acid Hydrazide(INH) useful in the treatment of tuberculosis. The invention relates to the single step conversion of isonicotinamide by hydrazine hydrate to Isonicotinic Acid Hydrazide (INH) of yield greater than 95% (w/w) and purity more than 99%.

Filing Date: 20-03-2003

Issue Date: 11-05-2004

Applicant: CSIR-Central Institute of Mining and Fuel Research (CSIR-CIMFR), Dhanbad

Patent No: US6734309

Application No: 10/393372

Inventor(s): Ray, Subhash Chandra (Dhanbad, In); Nandi, Lakshmi Narayan (Dhanbad, In); Singh, Baldev (Dhanbad, In); Prasad, Hiralal (Dhanbad, In); Maharaj, Sumant (Dhanbad, In); Sarkar, Prodyot Kumar (Dhanbad, In); Dutta, Pashupati (Dhanbad, In); Roy, Shyam Kishore (Dhanbad, In); Yadav, Satya Niketan (Dhanbad, In); Bandyopadhyay, Anup Kumar (Dhanbad, In)

IPC Classification: C07D 213/56

Country: United States of America

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