Executive Summary : | The current proposal highlights a unique CC bond forming reaction between vinyl azides and various in situ generated iminium intermediates under transition metal free conditions. Moreover, the proposed reactions may proceed under mild reaction conditions and yield a number of valuable cyclic/acyclic amines under a redox-neutral atmosphere. Notably, the reaction may proceed via direct insertion of metheyleneamino unit into vinyl azides followed by Schmidt-type reaction and 1,5-hydride transfer sequence. In addition, a straightforward and single step strategy to install methyleneamino unit at - position of saturated N-heterocycle is predicted. Furthermore, asymmetric transformation between vinyl azides and aminals to yield enantiopure amines is anticipated. |