Cognitive Sciences and Psychology
Title : | Cognitive control and brain connectivity as predictors of psychotherapy response in common mental disorders |
Area of Research : | Cognitive Sciences and Psychology |
Focus Area : | Cognitive Neuroscience |
Principal Investigator : | Dr. Himani Kashyap, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka (560029) |
Co-PI: | Dr. Manjula M, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka (560029), Dr. Rajakumari P Reddy, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka (560029), Dr. Rose Dawn Bharath, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka (560029), Dr. Urvakhsh Meherwan Mehta, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka (560029) |
Contact info : | Dr.himanikashyap@gmail.com;
drmanjula71@gmail.com;
rajkumarireddy227@gmail.com;
drrosedawnbharath@gmail.com;
urvakhsh@gmail.com |
Timeline Start Year : | 2023 |
Timeline End Year : | 2026 |
Total Budget (INR): | 31,21,410 |
Details
Executive Summary : | Common mental disorders (CMDs), such as depression and anxiety disorders, are prevalent worldwide and cause significant disability and burden. Despite evidence-based treatments, approximately 50 of individuals receiving either psychotherapy or pharmacotherapy do not achieve remission. In India, there is a treatment gap of up to 85 for CMDs. Cognitive control, the effortful use of cognitive resources for flexible adjustment, has emerged as a transdiagnostic vulnerability factor. Cognitive control has been suggested as a predictive factor of pharmacotherapy outcomes in some disorders. Up to 40 of psychotherapy outcome is explained by "client variables," such as regular attendance, engagement versus avoidance/resistance, collaboration, and self-initiative. However, little is understood about enhancing psychotherapy response. Cognitive control may be subserved by effortful regulation of emotion, cognition, and behavior. Neuroplastic changes observed pre-post psychotherapy for CMDs also corroborate improved cognitive control, suggesting effortful regulation of habitual emotional responses. The role of cognitive control in predicting and mediating psychotherapy outcomes in CMDs is not widely studied. Few studies investigating cognitive control in psychotherapy outcomes investigate geriatric samples, showing mixed findings. The present study aims to investigate the role of cognitive control as a predictor of psychotherapy response in CMDs. The sample will include 90 individuals with CMD allocated to two groups: an intervention group with 60 transdiagnostic psychotherapy protocol for 12 weeks and a control group with 30 individuals unable to attend psychotherapy. Impacts of investigating cognitive control as a predictor of response may include developing interventions for individuals lower in cognitive control, cognitive control training as an adjunct/prerequisite to psychotherapy, developing low-intensity interventions, or self-help resources for large-scale delivery, and streamlining intensity of interventions based on predictors of response. |
Equipments : | Nil ( Rs.0.00 ) , Nil ( Rs.0.00 ) , Nil ( Rs.0.00 ) |
Organizations involved