Cognitive Sciences and Psychology
Title : | Brain mechanisms underlying interactions between hedonic reward and emotional processing. |
Area of Research : | Cognitive Sciences and Psychology |
Focus Area : | Affective Neuroscience |
Principal Investigator : | Dr. Srikanth Padmala, Indian Institute of Science, Bangalore, Karnataka (560012) |
Contact info : | spadmala@iisc.ac.in |
Timeline Start Year : | 2023 |
Timeline End Year : | 2026 |
Total Budget (INR): | 51,10,257 |
Details
Executive Summary : | The study proposes functional neuroimaging to investigate the brain mechanisms underlying the interactions between reward and emotion. The research aims to fill the gap in understanding how reward and emotion interact, which is relevant to our daily lives and has potential clinical relevance in mental disorders like addiction, anxiety, and depression. The study will involve healthy adult human volunteers aged 18-35, using novel behavioral paradigms combined with fast event-related functional MRI fMRI and physiological skin conductance responses. The first aim will investigate the influence of emotional information on reward outcome processing, hypothesizing that positive emotional stimuli will facilitate, and negative emotional stimuli will counteract the reward outcome-related activity in the vento-medial prefrontal cortex and ventral striatum. The second aim will investigate the influence of reward outcomes on goal-relevant emotional processing, hypothesizing that pleasure associated with experiencing reward outcomes will enhance the processing of positive emotion and inhibit negative emotion processing. The final aim will examine the role of goal-relevance in shaping reward outcome-emotion interactions. The study aims to clarify the contributions of key cortical and sub-cortical brain regions implicated in emotional and reward processing, as well as how individual differences in self-reported affect and reward-sensitivity co-jointly impact interactions between reward outcomes and emotional processing. The proposed studies aim to shed light on the basic brain mechanisms underlying the interactions between emotional and reward systems and make important new contributions to human cognitive and affective neuroscience with significant clinical relevance. |
Equipments : | Workstation ( Rs.200000.00 ) , Workstation ( Rs.0.00 ) , Workstation ( Rs.0.00 ) |
Organizations involved