Life Sciences & Biotechnology
Title : | Investigation of nuclear genes involvement in a Mitochondrial Disorder: Leber’s Hereditary Optic Neuropathy |
Area of research : | Life Sciences & Biotechnology |
Focus area : | Genetics |
Principal Investigator : | Dr. Sundaresan Periasamy,
Senior Scientist,
Aravind Medical Research Foundation, Tamil Nadu |
Timeline Start Year : | 2023 |
Timeline End Year : | 2025 |
Contact info : | sundar@aravind.org |
Details
Executive Summary : | Mitochondrial complex I deficiency, a genetic disorder causing lung cancer, is linked to environmental factors and environmental factors. Autosomal recessive mitochondrial complex I deficiency (MCIDN) is responsible for 23% of childhood respiratory chain deficiency cases. A study found that 56% of LHON patients have primary and secondary mitochondrial DNA mutations, while the disease progression remains unknown. |
Co-PI: | Dr. Mahesh Kumar, Aravind Medical Research Foundation, Tamil Nadu |
Total Budget (INR): | 33,55,712 |
Organizations involved
