Research
Title : | Process Development of Risdiplam, Cladribine and Palovarotene Drugs for Rare/Orphan Diseases |
Area of Research : | Pharmaceutical Sciences |
Focus Area : | Chemical Engineering |
Principal Investigator : | Dr. Raju Adepu, CSIR- Indian Institute of Chemical Technology, Hyderabad, Telangana (500007) |
Co-PI: | Dr. Nayani Kiranmai, CSIR-Indian Institute of Chemical Technology (IICT), Telangana (500076) |
Contact info : | rajuadepu@iict.res.in; kiranmainayani@iict.res.in |
Total Budget (INR): | 74,52,000 |
Details
Executive Summary : | Rare diseases are prevalent in a small number of populations and there is a deficit of medicines. In India, there is an existence of nearly 450 rare diseases, and it has become a challenge to treat these diseases due to poor diagnosis lack of proper treatment options. There is tremendous pressure toward the initiation of research and development in orphan drug discovery. Based on the importance of orphan drug diseases we aimed to develop synthetic process for rare disease drugs such as risdiplam, cladribine, and palovarotene. It is planned to develop a process and technology transfer to start-up company for large-scale production and commercialization. |
Organizations involved
Implementing Agency : | CSIR- Indian Institute of Chemical Technology, Hyderabad, Telangana Funding Agency :Department of Science and Technology (DST) | Source:Department of Science and Technology (DST) | |