Research
Title : | Investigating the mechanism of Insulin-dependent regulation of RAB4-associated vesicular transport in axons |
Area of Research : | Medical Sciences |
Principal Investigator : | Prof. Krishanu Ray, Professor, Tata Institute of Fundamental Research (TIFR), Mumbai |
Contact info : | krishanu@tifr.res.in |
Timeline Start Year : | 2021 |
Associated Programme / Scheme : | Core Research Grant (CRG) |
Total Budget (INR): | 57,22,080 |
Details
Executive Summary : | This project proposes to employ a combination of in vitro and in vivo approaches to identify a) how RAB4 recruits kinesins after insulin stimulation, b) how RAB4 vesicles move with an increased speed upon insulin stimulation, and c) the effects of the increased flux of RAB4 vesicle movement on the synapse homeostasis. |
Organizations involved
Implementing Agency : | Tata Institute of Fundamental Research (TIFR), Mumbai Funding Agency :Science and Engineering Research Board (SERB), Department of Science and Technology (DST) | |