Chemical Sciences, Pharmaceutical Sciences


Superoxide Dismutase (SOD)


Chemical Sciences, Pharmaceutical Sciences

Focus Area:

Dismutase Catalyzation


US6485950, US7037697

Social Benefits:

Unique features of CSIR-IHBT SOD , SOD tolerates autoclaving [retains~75% of the un-autoclaved activity (specific activity) as measured at 5°C to 10°C], It functions across 0°C to 50°C with varying activities at different assay temperatures, Stable at room temperature, SOD has high demand in cosmetic, food and pharmaceutical industries for end applications, like developing anti-ageing creams, extending shelf-life of fruits and vegetables and during cryo-surgery and preservation of organelles.

Developing Agency:

CSIR-Institute of Himalayan Bioresource Technology (IHBT), Himachal Pradesh

Technology Readiness Index:

Market Launch

Website Link :
Source (more info) :

Brief Description

Description :

Contributions of CSIR-IHBT . A thermostable SOD has been identified from a Himalayan polyextremophile plant Potentilla atrosanguinea, which was further engineered by mutation of a single amino acid to enhance the thermostability of the enzyme to twofold. An in vitro expression system was developed in E. coli for enzyme production at pilot scale.

Related Technologies