Life Sciences & Biotechnology

Title :

Research in ASTHI: Pre-clinical development of CDRI optimized lead molecules as dual osteogenic and muscle anabolic agents

Area of research :

Life Sciences & Biotechnology, Medical Sciences

Focus area :


Principal Investigator :

Dr Naibedya Chattopadhyay, Scientist, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow

Timeline Start Year :


Timeline End Year :


Contact info :


Executive Summary :

Objective: Nature-inspired synthesis of medicarpin and their derivativities as a novel dual-acting drug candidate for the treatment of osteoporosis: preclinical development. Evaluation of CDRI osteogenic lead medicarpin (water-soluble salt) in skeletal muscle atrophy. Engineered self-assembled composites bearing medicarpinl potential osteogenic agents for spatial drug targeting and bone regeneration.

Organizations involved